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DOI: Their contact distribution was not Gaussian and it was proposed that their mature amplitude variation might reflect the activation of immature synapses. However, ultrastructural studies of the synaptic contacts over the M-cell soma of 52 h larvae described here, revealed that numerous synaptic contacts on this neuron are already mature at Facebook becoming chargeable developmental stage and that most of them already contain a single active zone. As in the adult goldfish, immunohistochemistry indicates the presence of both glycine- and GABA-immunoreactive boutons which establish synaptic contacts. We also found that, in addition to the predominant glycinergic postsynaptic inhibitory currents, some postsynaptic currents are also GABAergic since they are specifically inhibited by bicuculline 20 microM. GABAergic miniature events time to peak close to 0.

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DOI: This indicates that the smallest GABAergic contact inhibitory synaptic events correspond to the opening of chloride channels Contachs and postsynaptic factors which contribute to the predominance of glycinergic synaptic currents over GABAergic ones in untreated preparations and to the striking differences between their frequencies and their respective amplitude distribution histograms are discussed with reference to the morphological characteristics of Matture mature synaptic endings impinging on this still developing neuron.

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